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1

The spike protein of SARS-CoV — a target for vaccine and therapeutic development

Du, Lanying, He, Yuxian, Zhou, Yusen, Liu, Shuwen, Zheng, Bo-Jian, Jiang, Shibo

Journal:

Nature Reviews Microbiology

Year:

2009

Language:

english

File:

PDF, 994 KB

english, 2009

2

Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China

Yu, Fei, Du, Lanying, Ojcius, David M., Pan, Chungen, Jiang, Shibo

Journal:

Microbes and Infection

Year:

2020

Language:

english

File:

PDF, 4.88 MB

english, 2020

3

MERS-CoV spike protein: a key target for antivirals

Du, Lanying, Yang, Yang, Zhou, Yusen, Lu, Lu, Li, Fang, Jiang, Shibo

Journal:

Expert Opinion on Therapeutic Targets

Year:

2017

Language:

english

File:

PDF, 1.52 MB

english, 2017

4

Molecular mechanism for antibody-dependent enhancement of coronavirus entry

Wan, Yushun, Shang, Jian, Sun, Shihui, Tai, Wanbo, Chen, Jing, Geng, Qibin, He, Lei, Chen, Yuehong, Wu, Jianming, Shi, Zhengli, Zhou, Yusen, Du, Lanying, Li, Fang

Journal:

Journal of Virology

Year:

2019

File:

PDF, 1.12 MB

2019

5

Research and development of universal influenza vaccines

Lanying Du, Yusen Zhou, Shibo Jiang

Journal:

Microbes and Infection

Year:

2010

Language:

english

File:

PDF, 284 KB

english, 2010

6

Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection

Lanying Du, Guangyu Zhao, Yongping Lin, Chris Chan, Yuxian He, Shibo Jiang, Changyou Wu, Dong-Yan Jin, Kwok-Yung Yuen, Yusen Zhou, Bo-Jian Zheng

Journal:

Year:

2008

Language:

english

File:

PDF, 775 KB

english, 2008

7

Cause's attributes influencing consumer's purchasing intention: empirical evidence from China

Hou, Jundong, Du, Lanying, Li, Jianfeng

Journal:

Asia Pacific Journal of Marketing and Logistics

Year:

2008

Language:

english

File:

PDF, 128 KB

english, 2008

8

Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection

Channappanavar, Rudragouda, Lu, Lu, Xia, Shuai, Du, Lanying, Meyerholz, David K., Perlman, Stanley, Jiang, Shibo

Journal:

The Journal of Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

9

Prospects for a MERS-CoV spike vaccine

Zhou, Yusen, Jiang, Shibo, Du, Lanying

Journal:

Expert Review of Vaccines

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

10

Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity

Lanying Du, Guangyu Zhao, Chris C.S. Chan, Shihui Sun, Min Chen, Zhonghua Liu, Hongxiang Guo, Yuxian He, Yusen Zhou, Bo-Jian Zheng, Shibo Jiang

Journal:

Year:

2009

Language:

english

File:

PDF, 367 KB

english, 2009

11

The effects of nonprofit brand equity on individual giving intention: mediating by the self-concept of individual donor

Jundong Hou, Lanying Du, Zhilong Tian

Journal:

International Journal of Nonprofit and Voluntary Sector Marketing

Year:

2009

Language:

english

File:

PDF, 131 KB

english, 2009

12

Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines

Lanying Du, Yuxian He, Yijia Wang, Haojie Zhang, Selene Ma, Charlotte K.L. Wong, Sharon H.W. Wu, Fai Ng, Jian-Dong Huang, Kwok-Yung Yuen, Shibo Jiang, Yusen Zhou, Bo-Jian Zheng

Journal:

Year:

2006

Language:

english

File:

PDF, 550 KB

english, 2006

13

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

Tai, Wanbo, He, Lei, Zhang, Xiujuan, Pu, Jing, Voronin, Denis, Jiang, Shibo, Zhou, Yusen, Du, Lanying

Journal:

Cellular & Molecular Immunology

Year:

2020

Language:

english

File:

PDF, 2.99 MB

english, 2020

14

Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus

Yang, Yang, Liu, Chang, Du, Lanying, Jiang, Shibo, Shi, Zhengli, Baric, Ralph S., Li, Fang, Perlman, S.

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

15

Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infection

Qiu, Hongjie, Sun, Shihui, Xiao, He, Feng, Jiannan, Guo, Yan, Tai, Wanbo, Wang, Yufei, Du, Lanying, Zhao, Guangyu, Zhou, Yusen

Journal:

Antiviral Research

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

16

Identification and characterization of novel neutralizing epitopes in the receptor-binding domain of SARS-CoV spike protein: Revealing the critical antigenic determinants in inactivated SARS-CoV vaccine

Yuxian He, Jingjing Li, Lanying Du, Xuxia Yan, Guangan Hu, Yusen Zhou, Shibo Jiang

Journal:

Year:

2006

Language:

english

File:

PDF, 494 KB

english, 2006

17

Potential strategies and biosafety protocols used for dual-use research on highly pathogenic influenza viruses

Lanying Du, Ye Li, Jimin Gao, Yusen Zhou, Shibo Jiang

Journal:

Reviews in Medical Virology

Year:

2012

Language:

english

File:

PDF, 138 KB

english, 2012

18

Cryo-EM structure of porcine delta coronavirus spike protein in the pre-fusion state

Shang, Jian, Zheng, Yuan, Yang, Yang, Liu, Chang, Geng, Qibin, Tai, Wanbo, Du, Lanying, Zhou, Yusen, Zhang, Wei, Li, Fang

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 4.58 MB

english, 2017

19

Rational design of Zika virus subunit vaccine with enhanced efficacy

Tai, Wanbo, Chen, Jiawei, Zhao, Guangyu, Geng, Qibin, He, Lei, Chen, Yuehong, Zhou, Yusen, Li, Fang, Du, Lanying

Journal:

Journal of Virology

Year:

2019

File:

PDF, 4.83 MB

2019

20

Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses

Jiang, Shibo, Hillyer, Christopher, Du, Lanying

Journal:

Trends in Immunology

Year:

2020

File:

PDF, 1.03 MB

2020

21

Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments—The importance of immunofocusing in subunit vaccine design

Ma, Cuiqing, Wang, Lili, Tao, Xinrong, Zhang, Naru, Yang, Yang, Tseng, Chien-Te K, Li, Fang, Zhou, Yusen, Jiang, Shibo, Du, Lanying

Journal:

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

22

Advancements in the development of subunit influenza vaccines

Zhang, Naru, Zheng, Bo-Jian, Lu, Lu, Zhou, Yusen, Jiang, Shibo, Du, Lanying

Journal:

Microbes and Infection

Year:

2015

Language:

english

File:

PDF, 878 KB

english, 2015

23

In silico design of a DNA-based HIV-1 multi-epitope vaccine for Chinese populations

Yang, Yi, Sun, Weilai, Guo, Jingjing, Zhao, Guangyu, Sun, Shihui, Yu, Hong, Guo, Yan, Li, Jungfeng, Jin, Xia, Du, Lanying, Jiang, Shibo, Kou, Zhihua, Zhou, Yusen

Journal:

Human Vaccines & Immunotherapeutics

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

24

The latest advancements in Zika virus vaccine development

Du, Lanying, Zhou, Yusen, Jiang, Shibo

Journal:

Expert Review of Vaccines

Year:

2017

Language:

english

File:

PDF, 721 KB

english, 2017

25

Rational design of Zika virus subunit vaccine with enhanced efficacy

Tai, Wanbo, Chen, Jiawei, Zhao, Guangyu, Geng, Qibin, He, Lei, Chen, Yuehong, Zhou, Yusen, Li, Fang, Du, Lanying

Journal:

Journal of Virology

Year:

2019

Language:

english

File:

PDF, 4.83 MB

english, 2019

26

Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity

Lanying Du, Richard Y. Kao, Yusen Zhou, Yuxian He, Guangyu Zhao, Charlotte Wong, Shibo Jiang, Kwok-Yung Yuen, Dong-Yan Jin, Bo-Jian Zheng

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 343 KB

english, 2007

27

Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection

Wang, Yufei, Tai, Wanbo, Yang, Jie, Zhao, Guangyu, Sun, Shihui, Tseng, Chien-Te K., Jiang, Shibo, Zhou, Yusen, Du, Lanying, Gao, Jimin

Journal:

Human Vaccines & Immunotherapeutics

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

28

A Recombinant Vaccine of H5N1 HA1 Fused with Foldon and Human IgG Fc Induced Complete Cross-Clade Protection against Divergent H5N1 Viruses

Du, Lanying, Leung, Virtual Ho-Chuen, Zhang, Xiujuan, Zhou, Jie, Chen, Min, He, Wu, Zhang, Hai-Ying, Chan, Chris C. S., Poon, Vincent Kwok-Man, Zhao, Guangyu, Sun, Shihui, Cai, Lifeng, Zhou, Yusen, Zh

Journal:

Year:

2011

Language:

english

File:

PDF, 535 KB

english, 2011

29

An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses

Guangyu Zhao, Yongping Lin, Lanying Du, Jie Guan, Shihui Sun, Hongyan Sui, Zhihua Kou, Chris CS Chan, Yan Guo, Shibo Jiang, Bo-Jian Zheng, Yusen Zhou

Journal:

Virology Journal

Year:

2010

Language:

english

File:

PDF, 2.47 MB

english, 2010

30

[IEEE 2011 International Conference on Computer Science and Service System (CSSS) - Nanjing, China (2011.06.27-2011.06.29)] 2011 International Conference on Computer Science and Service System (CSSS) - Competitive environment of exclusively nonprofit organization marketplaces: Based on the framework of five forces

Jundong Hou,, Jun Lv,, Lanying Du,

Year:

2011

File:

PDF, 302 KB

2011

31

Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2

Tai, Wanbo, Zhang, Xiujuan, He, Yuxian, Jiang, Shibo, Du, Lanying

Journal:

Antiviral Research

Year:

2020

File:

PDF, 8.35 MB

2020

32

Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies

Lanying Du, Guangyu Zhao, Xiujuan Zhang, Zhonghua Liu, Hong Yu, Bo-Jian Zheng, Yusen Zhou, Shibo Jiang

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 468 KB

english, 2010

33

An H5N1 M2e-based multiple antigenic peptide vaccine confers heterosubtypic protection from lethal infection with pandemic 2009 H1N1 virus

Guangyu Zhao, Shihui Sun, Lanying Du, Wenjun Xiao, Zhitao Ru, Zhihua Kou, Yan Guo, Hong Yu, Shibo Jiang, Yuchun Lone, Bo-Jian Zheng, Yusen Zhou

Journal:

Virology Journal

Year:

2010

Language:

english

File:

PDF, 631 KB

english, 2010

34

A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

Zhao, Guangyu, Du, Lanying, Ma, Cuiqing, Li, Ye, Li, Lin, Poon, Vincent KM, Wang, Lili, Yu, Fei, Zheng, Bo-Jian, Jiang, Shibo, Zhou, Yusen

Journal:

Virology Journal

Year:

2013

Language:

english

File:

PDF, 306 KB

english, 2013

35

Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines

Ma, Cuiqing, Li, Ye, Wang, Lili, Zhao, Guangyu, Tao, Xinrong, Tseng, Chien-Te K., Zhou, Yusen, Du, Lanying, Jiang, Shibo

Journal:

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

36

Recent Advances in the Development of Virus-Like Particle-Based Flavivirus Vaccines

Zhang, Naru, Li, Chaoqun, Jiang, Shibo, Du, Lanying

Journal:

Year:

2020

File:

PDF, 523 KB

2020

37

A role for complement in paraquat-induced acute lung injury

Shihui Sun, Hanbin Wang, Guangyu Zhao, Yingbo An, Lanying Du, Hongbin Song, Yan Guo, Renfeng Guo, Shibo Jiang, Fei Qiao, Stephen Tomlinson, Yusen Zhou

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 84 KB

english, 2010

38

Development of SARS vaccines and therapeutics is still needed

Jiang, Shibo, Lu, Lu, Du, Lanying

Journal:

Future Virology

Year:

2013

Language:

english

File:

PDF, 478 KB

english, 2013

39

Cell entry of porcine epidemic diarrhea coronavirus is activated by lysosomal proteases

Liu, Chang, Ma, Yuanmei, Yang, Yang, Zheng, Yuan, Shang, Jian, Zhou, Yusen, Jiang, Shibo, Du, Lanying, Li, Jianrong, Li, Fang

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 3.03 MB

english, 2016

40

Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses

Jiang, Shibo, Hillyer, Christopher, Du, Lanying

Journal:

Trends in Immunology

Year:

2020

File:

PDF, 83 KB

2020

41

A Critical HA1 Neutralizing Domain of H5N1 Influenza in an Optimal Conformation Induces Strong Cross-Protection

Du, Lanying, Zhao, Guangyu, Sun, Shihui, Zhang, Xiujuan, Zhou, Xiaojun, Guo, Yan, Li, Ye, Zhou, Yusen, Jiang, Shibo, Xu, Jianqing

Journal:

Year:

2013

Language:

english

File:

PDF, 982 KB

english, 2013

42

Subunit Vaccines Against Emerging Pathogenic Human Coronaviruses

Wang, Ning, Shang, Jian, Jiang, Shibo, Du, Lanying

Journal:

Frontiers in Microbiology

Year:

2020

File:

PDF, 3.59 MB

2020

43

Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells

Lanying Du, Guangyu Zhao, Lin Li, Yuxian He, Yusen Zhou, Bo-Jian Zheng, Shibo Jiang

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 504 KB

english, 2009

44

Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model

Lanying Du, Guangyu Zhao, Yuxian He, Yan Guo, Bo-Jian Zheng, Shibo Jiang, Yusen Zhou

Journal:

Year:

2007

Language:

english

File:

PDF, 585 KB

english, 2007

45

Intranasal Administration of Maleic Anhydride-Modified Human Serum Albumin for Pre-Exposure Prophylaxis of Respiratory Syncytial Virus Infection

Sun, Zhiwu, Wang, Qian, Jia, Ran, Xia, Shuai, Li, Yuan, Liu, Qi, Xu, Wei, Xu, Jin, Du, Lanying, Lu, Lu, Jiang, Shibo

Journal:

Year:

2015

Language:

english

File:

PDF, 1.48 MB

english, 2015

46

Recombinant receptor-binding domains of multiple MERS-coronaviruses induce cross-neutralizing antibodies against divergent human and camel MERS-coronaviruses and antibody-escape mutants

Tai, Wanbo, Wang, Yufei, Fett, Craig A., Zhao, Guangyu, Li, Fang, Perlman, Stanley, Jiang, Shibo, Zhou, Yusen, Du, Lanying

Journal:

Journal of Virology

Year:

2016

Language:

english

File:

PDF, 6.00 MB

english, 2016

47

Treatment of Paraquat-Induced Lung Injury With an Anti-C5a Antibody

Sun, Shihui, Jiang, Yuting, Wang, Renxi, Liu, Chenfeng, Liu, Xiaoling, Song, Nianping, Guo, Yan, Guo, Renfeng, Du, Lanying, Jiang, Shibo, Li, Yan, Qiu, Zewu, Zhao, Guangyu, Zhou, Yusen

Journal:

Critical Care Medicine

Year:

2018

Language:

english

File:

PDF, 469 KB

english, 2018

48

Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome

Jiang, Shibo, Bottazzi, Maria Elena, Du, Lanying, Lustigman, Sara, Tseng, Chien-Te Kent, Curti, Elena, Jones, Kathryn, Zhan, Bin, Hotez, Peter J

Journal:

Expert Review of Vaccines

Year:

2012

Language:

english

File:

PDF, 981 KB

english, 2012

49

Development of a heat-stable and orally delivered recombinant M2e-expressing B. subtilis spore-based influenza vaccine

Zhao, Guangyu, Miao, Yu, Guo, Yan, Qiu, Hongjie, Sun, Shihui, Kou, Zhihua, Yu, Hong, Li, Junfeng, Chen, Yue, Jiang, Shibo, Du, Lanying, Zhou, Yusen

Journal:

Human Vaccines & Immunotherapeutics

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

50

Approaches for Identification of HIV-1 Entry Inhibitors Targeting gp41 Pocket

Yu, Fei, Lu, Lu, Du, Lanying, Zhu, Xiaojie, Debnath, Asim, Jiang, Shibo

Journal:

Year:

2013

Language:

english

File:

PDF, 575 KB

english, 2013

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